diff --git a/crates/dbx-core/src/db/mysql.rs b/crates/dbx-core/src/db/mysql.rs
index 059a00e4fa..48e9a624c6 100644
--- a/crates/dbx-core/src/db/mysql.rs
+++ b/crates/dbx-core/src/db/mysql.rs
@@ -5766,12 +5766,12 @@ fn mysql_statistics_expression_is_unsupported(error: &mysql_async::Error) -> boo
     match error {
         mysql_async::Error::Server(server_error) if server_error.code == 1054 => true,
         mysql_async::Error::Server(server_error)
-            if server_error.code == 3009 && server_error.state.eq_ignore_ascii_case("HY000") =>
+            if matches!(server_error.code, 3009 | 4518) && server_error.state.eq_ignore_ascii_case("HY000") =>
         {
-            // PolarDB-X/DRDS wraps the unknown EXPRESSION column in TDDL error
-            // 3009. Require the complete diagnostic so unrelated HY000 errors
-            // (for example permissions or connectivity failures) are not retried
-            // with a different metadata query.
+            // PolarDB-X/DRDS wraps the unknown EXPRESSION column in optimizer
+            // errors (4518/PXC and 3009/TDDL). Require the complete diagnostic
+            // so unrelated HY000 errors (for example permissions or connectivity
+            // failures) are not retried with a different metadata query.
             let message = server_error.message.to_ascii_lowercase();
             message.contains("column") && message.contains("expression") && message.contains("not found")
         }
@@ -7766,6 +7766,29 @@ mod tests {
         assert!(!mysql_statistics_expression_is_unsupported(&wrong_state));
     }
 
+    #[test]
+    fn mysql_index_metadata_accepts_polardbx_expression_error_only_with_matching_message() {
+        let unsupported = mysql_async::Error::Server(mysql_async::ServerError {
+            code: 4518,
+            message: "[PXC-4518][ERR_VALIDATE] : Column 'EXPRESSION' not found in any table".to_string(),
+            state: "HY000".to_string(),
+        });
+        let unrelated = mysql_async::Error::Server(mysql_async::ServerError {
+            code: 4518,
+            message: "[PXC-4518][ERR_VALIDATE] : Column 'INDEX_NAME' not found in any table".to_string(),
+            state: "HY000".to_string(),
+        });
+        let wrong_state = mysql_async::Error::Server(mysql_async::ServerError {
+            code: 4518,
+            message: "[PXC-4518][ERR_VALIDATE] : Column 'EXPRESSION' not found in any table".to_string(),
+            state: "42S22".to_string(),
+        });
+
+        assert!(mysql_statistics_expression_is_unsupported(&unsupported));
+        assert!(!mysql_statistics_expression_is_unsupported(&unrelated));
+        assert!(!mysql_statistics_expression_is_unsupported(&wrong_state));
+    }
+
     #[test]
     fn mysql_group_concat_not_supported_error_retries_without_session_variable() {
         let error =